| CPC G01J 3/2823 (2013.01) [A61B 1/000094 (2022.02); A61B 1/000096 (2022.02); G06V 10/58 (2022.01); H04N 9/73 (2013.01); H04N 23/555 (2023.01); H04N 23/843 (2023.01)] | 12 Claims |

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1. A method of determining parameters of a desired target image from hyperspectral imagery obtained from a surgical procedure, comprising:
capturing in real time hyperspectral snapshot mosaic images of a scene from the surgical procedure using a hyperspectral image sensor coupled to an optical scope, the snapshot mosaic images being of relatively low spatial and low spectral resolution;
undertaking spatio-spectrally aware demosaicking of the snapshot mosaic images, the demosaicking comprising an algorithm to optimise for a cost function accounting for spatial crosstalk across neighbouring pixels corresponding to different spectral bands in the snapshot mosaic image, upsampling of the snapshot mosaic images, and the application of a spectral calibration operator, to generate a virtual hypercube of the snapshot mosaic image data, the virtual hypercube comprising image data of relatively high spatial resolution compared to the snapshot mosaic images;
from the image data in the virtual hypercube, determining relatively high spatial resolution parameters of a desired target image; and
outputting in real time the determined relatively high-resolution parameters as representative of the desired target image.
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