US 12,331,354 B2
DNA array
Radoje Drmanac, Los Altos Hills, CA (US); Matthew J. Callow, Redwood City, CA (US); Snezana Drmanac, Los Altos Hills, CA (US); Brian K. Hauser, Campbell, CA (US); and George Yeung, Mountain View, CA (US)
Assigned to Complete Genomics, Inc., San Jose, CA (US)
Filed by Complete Genomics, Inc, San Jose, CA (US)
Filed on Mar. 1, 2024, as Appl. No. 18/592,885.
Application 18/592,885 is a continuation of application No. 17/522,708, filed on Nov. 9, 2021.
Application 17/522,708 is a continuation of application No. 16/994,343, filed on Aug. 14, 2020, abandoned.
Application 16/994,343 is a continuation of application No. 16/425,846, filed on May 29, 2019, abandoned.
Application 16/425,846 is a continuation of application No. 15/442,659, filed on Feb. 25, 2017, granted, now 10,351,909, issued on Jul. 16, 2019.
Application 15/442,659 is a continuation of application No. 14/714,133, filed on May 15, 2015, granted, now 9,650,673, issued on May 16, 2017.
Application 14/714,133 is a continuation of application No. 12/882,880, filed on Sep. 15, 2010, abandoned.
Application 12/882,880 is a continuation of application No. 11/451,691, filed on Jun. 13, 2006, granted, now 8,445,194, issued on May 21, 2013.
Claims priority of provisional application 60/776,415, filed on Feb. 24, 2006.
Claims priority of provisional application 60/725,116, filed on Oct. 7, 2005.
Claims priority of provisional application 60/690,771, filed on Jun. 15, 2005.
Prior Publication US 2024/0301486 A1, Sep. 12, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. C12Q 1/6874 (2018.01); C07H 21/04 (2006.01); C07K 1/04 (2006.01); C12Q 1/6806 (2018.01); C12Q 1/682 (2018.01); C12Q 1/6837 (2018.01); C12Q 1/6869 (2018.01); G01N 15/1404 (2024.01); G01N 15/1434 (2024.01)
CPC C12Q 1/6874 (2013.01) [C07H 21/04 (2013.01); C07K 1/047 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/682 (2013.01); C12Q 1/6837 (2013.01); C12Q 1/6869 (2013.01); G01N 15/1404 (2013.01); G01N 15/1434 (2013.01); C12Q 2525/151 (2013.01); C12Q 2525/313 (2013.01); C12Q 2531/125 (2013.01); C12Q 2565/513 (2013.01); Y10S 977/778 (2013.01); Y10S 977/789 (2013.01); Y10S 977/792 (2013.01); Y10S 977/88 (2013.01); Y10S 977/882 (2013.01)] 19 Claims
 
1. An array of polynucleotide molecules on a surface,
wherein said surface comprises nucleotide binding regions separated by non-nucleotide binding regions arranged on the surface in a predetermined pattern;
wherein the nucleotide binding regions comprise nucleotide capture chemistry and the non-nucleotide binding regions do not have the nucleotide capture chemistry;
wherein more than 50% of the nucleotide binding regions in the array are occupied with a single one of the polynucleotide molecules; and
wherein said surface is not a bead.