| CPC C12N 1/04 (2013.01) [C12M 23/04 (2013.01); C12M 23/20 (2013.01); C12M 25/06 (2013.01); C12N 5/0068 (2013.01); C08L 83/04 (2013.01); C12N 2513/00 (2013.01); C12N 2533/30 (2013.01)] | 16 Claims |

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1. A surface-functionalized cell culture support, wherein the surface of the support material is modified by a transferred monolayer of polymerized striped phases of molecules comprising one or more chemical functional groups, one or more long alkyl chains, and one or more polymerizable functional groups; wherein said transferred striped monolayer is useful for modulating directional adhesion, proliferation, differentiation, or reprogramming of a cell wherein the spatially controlled arrangement of chemical functional groups of the striped phase occurs at a sub-10-nm scale for the spatial placement of those functional elements, wherein the spatial arrangement of the chemical functional groups of the striped monolayer mimic properties of polysaccharide components of an extracellular matrix useful for modulating adhesion, proliferation, differentiation, or reprogramming of a cell and wherein said chemical functional groups comprise a carbohydrate, Arg-Gly-Asp peptide or a functional analog thereof, a matrisome component, or a combination thereof.
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