US 12,331,272 B1
Ultra-high-cell-density multicellular tissue lifting bioprinting device assisted by oblique incident bulk wave and printing method therefor
Yuanjin Zhao, Nanjing (CN); and Zhuhao Wu, Nanjing (CN)
Assigned to NANJING DRUM TOWER HOSPITAL, Nanjing (CN)
Filed by NANJING DRUM TOWER HOSPITAL, Nanjing (CN)
Filed on Dec. 20, 2024, as Appl. No. 18/988,990.
Application 18/988,990 is a continuation of application No. PCT/CN2024/087486, filed on Apr. 12, 2024.
Claims priority of application No. 202410304987.X (CN), filed on Mar. 18, 2024.
Int. Cl. C12M 3/00 (2006.01); B29C 64/124 (2017.01); B29C 64/255 (2017.01); B33Y 10/00 (2015.01); B33Y 30/00 (2015.01); C12M 1/42 (2006.01)
CPC C12M 21/08 (2013.01) [B29C 64/124 (2017.08); B29C 64/255 (2017.08); B33Y 10/00 (2014.12); B33Y 30/00 (2014.12); C12M 35/04 (2013.01)] 16 Claims
 
1. An ultra-high-cell-density multicellular tissue lifting bioprinting device assisted by oblique incident bulk wave, comprising:
a printing liquid tank, a printing platform, a light source, and an oblique incident bulk wave chip, wherein
the printing liquid tank contains a printing liquid, wherein the printing liquid is a mixture of cells and a photocurable bioink;
the printing platform is arranged horizontally and extends into the printing liquid tank to come into contact with the printing liquid;
the printing platform is configured for going up and down;
the light source is arranged under the printing liquid tank, and light enters the printing liquid tank; and
the oblique incident bulk wave chip is a piezoelectric transducer arranged obliquely; and the piezoelectric transducer is arranged under the printing liquid tank and tilted relative to a horizontal plane to generate an oblique incident bulk wave acoustic field in the printing liquid.