US 12,331,083 B2
Immunogenic compositions to treat and prevent microbial infections
Clara J. Sei, Germantown, MD (US); Luke T. Daum, San Antonio, TX (US); and Gerald W. Fischer, Bethesda, MD (US)
Assigned to Longhorn Vaccines and Diagnostics, LLC, Bethesda, MD (US)
Filed by Longhorn Vaccines and Diagnostics, LLC, Bethesda, MD (US)
Filed on Dec. 4, 2023, as Appl. No. 18/527,937.
Application 18/527,937 is a continuation of application No. 17/161,997, filed on Jan. 29, 2021, granted, now 11,866,463.
Claims priority of provisional application 63/109,966, filed on Nov. 5, 2020.
Claims priority of provisional application 62/971,654, filed on Feb. 7, 2020.
Claims priority of provisional application 62/971,036, filed on Feb. 6, 2020.
Prior Publication US 2024/0166697 A1, May 23, 2024
Int. Cl. A61K 39/02 (2006.01); A61K 39/145 (2006.01); A61K 39/395 (2006.01); A61K 47/54 (2017.01); A61K 47/69 (2017.01); A61P 31/16 (2006.01); C07K 14/11 (2006.01); C07K 14/195 (2006.01); A61K 38/00 (2006.01)
CPC C07K 14/11 (2013.01) [A61K 39/02 (2013.01); A61K 39/145 (2013.01); A61K 39/395 (2013.01); A61K 47/543 (2017.08); A61K 47/549 (2017.08); A61K 47/6911 (2017.08); A61P 31/16 (2018.01); C07K 14/195 (2013.01); A61K 38/00 (2013.01)] 18 Claims
 
1. An immunogenic peptide containing a plurality of microbial epitopes, wherein the plurality comprises one or more epitopes of a Mycobacterium and one or more epitopes of an influenza virus wherein the plurality is contained in a contiguous peptide sequence, and the immunogenic peptide contains one or more sequences selected from the group consisting of SEQ ID NOs. 3-8, 15, 20, 22-24, 29, 37, 46-48, and 61.