US 12,331,031 B2
Vaporizable alkaloid compositions and methods of use thereof
Charlotte L. Owen, Seguin, TX (US); Richard Avila, Jr., Prescott Valley, AZ (US); and Geoff W. Habicht, Phoenix, AZ (US)
Assigned to Ready Mix Naturals, LLC, Seguin, TX (US)
Filed by Ready Mix Naturals, LLC, Seguin, TX (US)
Filed on Mar. 1, 2024, as Appl. No. 18/593,597.
Application 18/593,597 is a continuation of application No. 18/227,815, filed on Jul. 28, 2023, granted, now 11,964,958.
Claims priority of provisional application 63/439,650, filed on Jan. 18, 2023.
Prior Publication US 2024/0246930 A1, Jul. 25, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. C07D 401/04 (2006.01); A24B 15/167 (2020.01); A24B 15/30 (2006.01)
CPC C07D 401/04 (2013.01) [A24B 15/167 (2016.11); A24B 15/301 (2013.01)] 26 Claims
 
1. A vaporizable alkaloid composition, comprising:
at least one substituted pyridine compound of Formula (I), or salt or mixed salt thereof;

OG Complex Work Unit Chemistry
wherein R5 is CH3, and R1, R2, R3, and R4 are independently selected from alkyl, H, substituted alkyl, cycloalkyl, substituted cycloalkyl, alkenyl, and substituted alkenyl, with the proviso that at least one of R1, R2, R3, and R4 is not H,
at least one flavoring agent selected from the group comprising geraniol, geranial, valeric acid, ethyl maltol, ethyl butyrate, ethyl acetate, maltol, ethyl 3-methyl-3-phenylglycidate, furaneol, methyl cyclopentenolone, methyl cyclopentenolone, ethyl cyclopentenolone, δ-decalactone, γ-decalactone, α-nonalactone, β-nonalactone, cis-3-hexanol, iso-amyl acetate, ethyl-2-methyl butyrate, butyric acid, ethyl butyrate, 2-methylbutyric acid, benzyl alcohol, ethyl hexanoate, benzaldehyde, iso-amyl isovalerate, hexanoic acid, ethyl propionate, γ-undecalactone, acetyl propionyl, raspberry ketone, furfural, 5-methylfurfural, maltol, 2-acetylpyrazine, 2,3,5-trimethylpyrazine, 2-acetylpyrrole, 2-isopropyl-4-methylthiazole, 2-isobutylthiazole, furfuryl mercaptan, thiomenthone, p-menthene-8-thiol, tropathiane, hexyl acetate and mixtures thereof wherein the vaporizable alkaloid composition is entirely devoid of (R) or (S) nicotine.