US 12,331,028 B2
Process for preparation of Anthranilamides
Digish Manubhai Panchal, Mumbai (IN); Jigar Kantilal Desai, Mumbai (IN); Jaidev Rajnikant Shroff, Mumbai (IN); and Vikram Rajnikant Shroff, Dubai (AE)
Assigned to UPL LTD, Haldia (IN)
Appl. No. 17/311,467
Filed by UPL LTD, Haldia (IN)
PCT Filed Dec. 6, 2019, PCT No. PCT/IB2019/060508
§ 371(c)(1), (2) Date Jun. 7, 2021,
PCT Pub. No. WO2020/136480, PCT Pub. Date Jul. 2, 2020.
Claims priority of application No. 201831048884 (IN), filed on Dec. 24, 2018.
Prior Publication US 2022/0024892 A1, Jan. 27, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. C07D 401/04 (2006.01)
CPC C07D 401/04 (2013.01) 2 Claims
 
1. A process for purifying chlorantraniliprole, said process comprising:
a) preparing an aqueous slurry of a reaction product mixture comprising chlorantraniliprole in aqueous conditions, wherein the reaction product mixture is formed by a reaction of a compound of formula III

OG Complex Work Unit Chemistry
with methylamine in an organic solvent selected from the group consisting of acetonitrile and ethyl acetate;
b) stirring the aqueous slurry at a temperature from 40° C. to 50° C. for one hour;
c) separating solids from the aqueous slurry;
d) optionally repeating steps a), b) and c); and
e) drying the solids to obtain a purified chlorantraniliprole having a purity of at least 97% from the reaction product mixture, wherein the aqueous slurry comprises water or a mixture of water and ethyl acetate admixed with the reaction product mixture to solubilize the impurities.