| CPC C07D 207/14 (2013.01) | 6 Claims |
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1. A compound of the formula I:
![]() wherein:
X is —O— or —NH—, or X may be a direct bond to R1;
Y is N or CH;
R1 is selected from:
(1) -C1-6alkyl, where the alkyl is unsubstituted or substituted with one to six substituents independently selected from R4, and
(2) -C3-6cycloalkyl, where the cycloalkyl is unsubstituted or substituted with one to six substituents independently selected from R4;
R2 is selected from:
(1) hydrogen,
(2) -C1-6alkyl, where the alkyl is unsubstituted or substituted with one to six substituents independently selected from R4,
(3) -C3-6cycloalkyl, where the cycloalkyl is unsubstituted or substituted with one to six substituents independently selected from R4,
(4) -phenyl, where the phenyl is unsubstituted or substituted with one to three substituents independently selected from R4, and
(5) -heteroaryl, where the heteroaryl is selected from: pyridyl, pyrimidinyl, and pyrazinyl, and the heteroaryl is unsubstituted or substituted with one to three substituents independently selected from R4;
R2a and R2b are independently selected from:
(1) hydrogen,
(2) hydroxyl,
(3) halogen, and
(4) -C1-6alkyl, where the alkyl is unsubstituted or substituted with one to six substituents independently selected from halogen;
R3 is phenyl, where the phenyl is unsubstituted or substituted with one to three substituents independently selected from R4,
R4 is selected from:
(1) hydroxyl,
(2) halogen,
(3) C1-6alkyl, which is unsubstituted or substituted with one to six fluoro,
(4) -C3-6cycloalkyl,
(5) —O-C1-6alkyl,
(6) —O (C═O)-C1-6 alkyl,
(7) —NH2,
(8) —NH-C1-6alkyl,
(9) —NO2,
(10) phenyl,
(11) —CO2H, and
(12) —CN;
or a pharmaceutically acceptable salt thereof.
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