	US 12,331,012 B2
	Organic catalyst for non-aqueous aldol condensation
Sung-Yu Ku, Lake Jackson, TX (US); Sally Demaio-Turner, Lake Jackson, TX (US); Wanglin Yu, Lake Jackson, TX (US); and Michael A Brammer, Freeport, TX (US)
Assigned to Dow Global Technologies LLC, Midland, MI (US)
Appl. No. 17/999,978
Filed by Dow Global Technologies LLC, Midland, MI (US)
PCT Filed May 27, 2021, PCT No. PCT/US2021/034461 § 371(c)(1), (2) Date Nov. 28, 2022, PCT Pub. No. WO2021/242987, PCT Pub. Date Dec. 2, 2021.
Claims priority of provisional application 63/032,147, filed on May 29, 2020.
Prior Publication US 2023/0303473 A1, Sep. 28, 2023
Int. Cl. C07C 45/45 (2006.01); B01J 27/24 (2006.01); B01J 31/02 (2006.01); C07C 45/49 (2006.01)

CPC C07C 45/49 (2013.01) [B01J 27/24 (2013.01); B01J 31/0259 (2013.01)]

15 Claims

1. A process comprising:

providing a first blend comprising nonanals, C₈olefins and C₇-C₉alkanes;

adding, to the first blend, a component selected from the group consisting of C₄aldehyde, C₅aldehyde, and combinations thereof to form a non-aqueous reaction mixture having an initial water content from 0 wt % to 10 wt % water;

introducing an organic base catalyst to the non-aqueous reaction mixture;

heating the non-aqueous reaction mixture to a temperature from 30° C. to 100° C. and cross-aldol condensing the non-aqueous reaction mixture; and

forming a cross-aldol product composed of a component selected from the group consisting of C₈enals, C₁₀enals, C₁₃enals, C₁₄enals, and C₁₈enals, and combinations thereof.