US 12,330,172 B2
Method of use of cellular component concentrator and filter apparatus
Christopher M. Bare, Naples, FL (US); Robert M. Harrison, IV, Naples, FL (US); Melissa S. Tucker, Estero, FL (US); and Abigail Nabors, Naples, FL (US)
Assigned to Arthrex, Inc., Naples, FL (US)
Filed by ARTHREX, INC., Naples, FL (US)
Filed on Sep. 19, 2022, as Appl. No. 17/947,664.
Application 17/947,664 is a continuation of application No. 15/554,889, granted, now 11,534,774, previously published as PCT/US2016/021699, filed on Mar. 10, 2016.
Claims priority of provisional application 62/131,045, filed on Mar. 10, 2015.
Prior Publication US 2023/0018329 A1, Jan. 19, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. B04B 7/18 (2006.01); A61K 35/14 (2015.01); B01L 3/00 (2006.01); B04B 3/08 (2006.01); B04B 5/10 (2006.01); B04B 11/04 (2006.01)
CPC B04B 7/18 (2013.01) [A61K 35/14 (2013.01); B01L 3/502 (2013.01); B04B 3/08 (2013.01); B04B 5/10 (2013.01); B04B 11/04 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/0803 (2013.01); B01L 2400/0409 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A method of producing a therapeutic fluid from a mammalian body fluid, the method comprising the steps of:
(a) adding the mammalian body fluid to a circular inner body fluid reservoir of a concentrator apparatus, wherein the concentrator apparatus comprises:
(i) the circular inner body fluid reservoir;
(ii) an effluent collection reservoir that encircles the circular inner body fluid reservoir; and
(iii) at least one filter element or membrane between the circular inner body fluid reservoir and the effluent collection reservoir, wherein the at least one filter element or membrane is removable;
(b) subjecting the concentrator apparatus to centrifugation; and
(c) removing the therapeutic fluid from the effluent collection reservoir of the concentrator apparatus, wherein the therapeutic fluid has an increased concentration, amount, or both of therapeutic factors as compared to the mammalian body fluid.