| CPC B01L 3/502715 (2013.01) [G01N 21/3581 (2013.01); G01N 21/554 (2013.01); B01L 2300/04 (2013.01); G01N 2021/5903 (2013.01)] | 13 Claims |

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1. A microfluidic sensor chip, comprising:
a body comprising a substrate and an upper cover, and the upper cover having at least one opening;
at least one microfluidic channel formed on the substrate and has a supporting surface, wherein the at least one microfluidic channel communicates with the at least one opening; and
a metamaterial layer coated on the supporting surface, wherein the metamaterial layer has a plurality of regions, and each region has a corresponding resonance pattern,
wherein the upper cover has a first recessed part recessed towards the substrate, and a projection of the first recessed part on the substrate covers projections of the regions on the substrate.
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