US 12,330,150 B2
System and apparatus for fluid sample delivery
Vicki Clare Farr, Hamilton (NZ); Paul Trevor Johnstone, Hamilton (NZ); and Robert Graham Orchard, Hamilton (NZ)
Assigned to S.C.R (Engineers) Limited, Netanya (IL)
Appl. No. 17/262,061
Filed by S.C.R. (Engineers) Limited, Netanya (IL)
PCT Filed Jul. 24, 2019, PCT No. PCT/NZ2019/050086
§ 371(c)(1), (2) Date Jan. 21, 2021,
PCT Pub. No. WO2020/022910, PCT Pub. Date Jan. 30, 2020.
Claims priority of application No. 744562 (NZ), filed on Jul. 24, 2018.
Prior Publication US 2021/0308665 A1, Oct. 7, 2021
Int. Cl. B01L 3/02 (2006.01); G01F 11/12 (2006.01); G01N 1/14 (2006.01); G01N 1/28 (2006.01); G01N 21/78 (2006.01); G01N 33/04 (2006.01); G01N 35/10 (2006.01)
CPC B01L 3/0293 (2013.01) [B01L 3/0262 (2013.01); G01F 11/125 (2013.01); G01N 1/14 (2013.01); G01N 1/2813 (2013.01); G01N 21/78 (2013.01); G01N 33/04 (2013.01); G01N 35/1011 (2013.01); G01N 35/1016 (2013.01); B01L 2200/0605 (2013.01); B01L 2200/141 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/069 (2013.01); B01L 2300/14 (2013.01); B01L 2400/024 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0605 (2013.01); G01N 2001/1427 (2013.01); G01N 2001/2826 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A system for analysing a fluid, including:
a sensing element configured to respond to at least one analyte in a sample of fluid;
a detector configured to sense a response to the analyte by the sensing element;
a fluid sample delivery apparatus, including:
a dosage needle configured to deliver the sample of fluid to the sensing element;
at least one pump configured to control flow of fluid through the dosage needle;
at least one actuator configured to move the dosage needle relative to the sensing element; and
a wicking feature configured to contact a drop of the same fluid as the sample of fluid suspended from the dosage needle when the dosage needle is in a predetermined position relative to the wicking feature; and
at least one controller configured to:
control the at least one actuator to position the dosage needle relative to the sensing element such that a gap is provided between at least a portion of an end of the dosage needle from which the sample of fluid is delivered and the sensing element;
control the at least one pump to deliver a predetermined volume of the sample of fluid to the sensing element through the dosage needle;
control the at least one pump to control aspiration of at least a portion of the sample of fluid back from the sensing element; and
prepare the sample of fluid in the dosage needle prior to delivery to the sensing element, including positioning the dosage needle proximate to the wicking feature, such that the drop of the same fluid as the sample of fluid is wicked away from the dosage needle by the wicking feature.
 
15. A method for analysing a fluid, including:
moving, using at least one actuator, a dosage needle of a fluid sample delivery device relative to a sensing element;
delivering a sample of fluid to the sensing element via the dosage needle by controlling at least one pump configured to control flow of fluid through the dosage needle, wherein the sensing element is configured to respond to at least one analyte in the sample of fluid; and
sensing, using a detector, a response to the at least one analyte by the sensing element, wherein delivering the sample of fluid includes:
preparing the sample of fluid in the dosage needle prior to delivery to the sensing element, wherein preparing the sample of fluid includes positioning the dosage needle proximate to a wicking feature, such that a drop of the same fluid as the sample of fluid formed on a tip of the dosage needle is wicked away from the dosage needle by the wicking feature;
positioning the dosage needle relative to the sensing element such that a gap is provided between at least a portion of an end of the dosage needle from which the sample of fluid is delivered and the sensing element;
delivering the sample of fluid as a predetermined volume of the sample of fluid to the sensing element through the dosage needle;
aspirating at least a portion of the sample of fluid back from the sensing element.