	US 12,330,138 B2
	Surface functionalised materials for sampling biological molecules
Paul Antonio Jones, London (GB)
Assigned to Paul Antonio Jones, London (GB)
Appl. No. 16/981,197
Filed by Paul Antonio Jones, London (GB)
PCT Filed Mar. 15, 2019, PCT No. PCT/GB2019/050736 § 371(c)(1), (2) Date Sep. 15, 2020, PCT Pub. No. WO2019/175599, PCT Pub. Date Sep. 19, 2019.
Claims priority of application No. 1804217 (GB), filed on Mar. 16, 2018.
Prior Publication US 2021/0023534 A1, Jan. 28, 2021
Int. Cl. A61B 10/00 (2006.01); B01J 20/10 (2006.01); B01J 20/28 (2006.01); B01J 20/30 (2006.01); B01J 20/32 (2006.01); G01N 33/50 (2006.01); G01N 33/68 (2006.01)

CPC B01J 20/28047 (2013.01) [A61B 10/0051 (2013.01); A61B 10/007 (2013.01); B01J 20/103 (2013.01); B01J 20/3085 (2013.01); B01J 20/3255 (2013.01); B01J 20/3257 (2013.01); B01J 20/3268 (2013.01); G01N 33/5005 (2013.01); G01N 33/6866 (2013.01); A61B 2010/0054 (2013.01); A61B 2010/0061 (2013.01); A61B 2010/0074 (2013.01); G01N 2333/555 (2013.01); G01N 2800/26 (2013.01)]

20 Claims

1. A surface-functionalised xerogel comprising a functional group that selectively binds to a biological molecule from a subject,

wherein the surface-functionalised xerogel is monolithic and configured to have a size and shape suitable for insertion into a body orifice, a body cavity, or a bodily tube, and for contacting a mucous membrane therein, thereby sampling the biological molecule from the subject, and

wherein the shape of the surface-functionalised xerogel is substantially that of a cylinder, a rod, a disk, a sphere, a cone, or a frustocone.