US 12,329,971 B2
Adaptation of neurostimulation therapy to age-related physiological changes
John Louis Parker, Artarmon (AU); Peter Scott Vallack Single, Artarmon (AU); Dean Michael Karantonis, Artarmon (AU); Matthew Marlon Williams, Artarmon (AU); Daniel John Parker, Artarmon (AU); and Samuel Nicholas Gilbert, Artarmon (AU)
Assigned to Saluda Medical Pty Ltd, Macquarie Park (AU)
Filed by Saluda Medical Pty Ltd, Artarmon (AU)
Filed on Jul. 15, 2022, as Appl. No. 17/812,959.
Claims priority of application No. 2021902202 (AU), filed on Jul. 16, 2021.
Prior Publication US 2023/0014405 A1, Jan. 19, 2023
Int. Cl. A61N 1/36 (2006.01)
CPC A61N 1/36139 (2013.01) 21 Claims
OG exemplary drawing
 
1. A method of adapting the operation of an implantable device for delivering neurostimulation therapy to a patient, the method comprising:
delivering the neurostimulation therapy to electrically excitable tissue of the patient according to at least one therapy parameter;
measuring a physiological characteristic of the patient;
adjusting the at least one therapy parameter according to a schedule of adjustment and the measured physiological characteristic; and
repeating the delivering, measuring, and adjusting;
wherein the adjusting the at least one therapy parameter comprises determining whether the measured physiological characteristic indicates physical ageing of the patient at a rate different from an expected rate, and adjusting the at least one therapy parameter according to the schedule of adjustments if the measured physiological characteristic does not indicate physical ageing of the patient at a rate different from the expected rate.