| CPC A61M 60/148 (2021.01) [A61B 5/02028 (2013.01); A61M 60/13 (2021.01); A61M 60/216 (2021.01); A61M 60/531 (2021.01); A61M 60/538 (2021.01); A61M 60/546 (2021.01); A61N 1/36571 (2013.01)] | 20 Claims |

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1. A system for cardiac support, the system comprising:
a heart pump comprising:
a first portion configured to be positioned within a left ventricle of a patient;
a second portion coupled to the first portion and configured to extend through an aortic valve of the patient and into an aorta of the patient when the first portion is positioned within the left ventricle of the patient; and
a first sensor positioned within the first portion of the heart pump and configured to generate an output used to measure or calculate a left ventricular systolic pressure (LVSP) within the left ventricle of the patient; and
a controller coupled to the heart pump and configured to measure or calculate the LVSP based on the output of the first sensor and to control an operation of the heart pump to mechanically unload the left ventricle of the patient based on the measured or calculated LVSP,
wherein the heart pump has a pump speed and a flow rate, and the controller is configured to control the pump speed or the flow rate of the heart pump, such that the LVSP within the left ventricle is maintained at a target reference pressure, and
wherein the controller is configured to set the target reference pressure to reduce a pressure-volume area (PVA) of the left ventricle;
by about 90% to about 97%.
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