US 12,329,955 B2
Intravascular membrane oxygenator catheter with oscillating hollow fiber membranes
Tobias Straube, Durham, NC (US); Stewart Farling, Durham, NC (US); Bruce Klitzman, Durham, NC (US); Marc Deshusses, Durham, NC (US); Travis Vesel, Durham, NC (US); and Ira Cheifetz, Durham, NC (US)
Assigned to Duke University, Durham, NC (US)
Filed by Duke University, Durham, NC (US)
Filed on Jul. 26, 2023, as Appl. No. 18/226,539.
Application 18/226,539 is a continuation of application No. 17/962,966, filed on Oct. 10, 2022, granted, now 11,771,883.
Claims priority of provisional application 63/254,208, filed on Oct. 11, 2021.
Prior Publication US 2023/0372694 A1, Nov. 23, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61M 60/122 (2021.01); A61M 60/13 (2021.01)
CPC A61M 60/122 (2021.01) [A61M 60/13 (2021.01)] 20 Claims
OG exemplary drawing
 
1. An intravascular gas exchange system, the system comprising:
a pneumatic inlet configured to couple to a pneumatic source that provides a gas at a pressure at or above 1.1 bar of absolute pressure;
a plurality of hollow fiber membranes (HFM) in pneumatic communication with the pneumatic inlet to receive the gas and with an outlet for exhaust gas,
wherein a diffusive flux of the gas flows from the plurality of HFMs in a region of interest of a subject, and
wherein an average intraluminal pressure in the plurality of HFMs is at or above 1.1 bar of absolute pressure;
a vacuum system pneumatically coupled to the plurality of HFMs; and
an electronic controller coupled to the vacuum system and configured to control the vacuum system to de-pressurize the plurality of HFMs in response to detecting that a pressure change value in the plurality of HFMs has exceeded a threshold.