| CPC A61M 5/16827 (2013.01) [A61M 5/145 (2013.01); A61M 5/16886 (2013.01); A61M 2005/14208 (2013.01); A61M 2202/0464 (2013.01); A61M 2205/3344 (2013.01); A61M 2205/3389 (2013.01); A61M 2210/0693 (2013.01)] | 15 Claims |

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1. A CSF management system for use with a patient having a body with CSF having a natural flow rate, the system comprising:
a CSF circuit configured to control flow of the CSF in the body;
a therapeutic input fluidly coupled with the CSF circuit and configured to receive a bolus of therapeutic material into the CSF circuit;
a pump configured to direct the therapeutic material, via the CSF circuit, toward a prescribed portion of the body; and
a controller configured to vary the flow of the CSF in the CSF circuit to localize the CSF at the prescribed portion of the body, wherein varying comprises oscillating a direction of the CSF flow between opposing directions within the CSF circuit to maintain therapeutic material in the prescribed portion of the body.
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