US 12,329,881 B2
Biological valve for venous insufficiency
Norman Jaffe, Dana Point, CA (US)
Assigned to enVVeno Medical Corporation, Irvine, CA (US)
Filed by enVVeno Medical Corporation, Irvine, CA (US)
Filed on Jan. 11, 2023, as Appl. No. 18/095,856.
Application 18/095,856 is a continuation of application No. 17/748,467, filed on May 19, 2022, granted, now 11,577,004.
Application 17/748,467 is a continuation of application No. 17/323,238, filed on May 18, 2021, granted, now 11,338,064, issued on May 24, 2022.
Application 17/323,238 is a continuation of application No. 15/711,314, filed on Sep. 21, 2017, granted, now 11,285,243, issued on Mar. 29, 2022.
Application 15/711,314 is a continuation of application No. 12/789,176, filed on May 27, 2010, abandoned.
Application 12/789,176 is a continuation of application No. 12/252,253, filed on Oct. 15, 2008, abandoned.
Claims priority of provisional application 60/980,708, filed on Oct. 17, 2007.
Prior Publication US 2023/0233741 A1, Jul. 27, 2023
Int. Cl. A61F 2/24 (2006.01); A61L 27/36 (2006.01); A61L 27/50 (2006.01)
CPC A61L 27/507 (2013.01) [A61F 2/2412 (2013.01); A61F 2/2415 (2013.01); A61F 2/2475 (2013.01); A61L 27/3625 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method to repair deep vein insufficiencies, comprising the steps of:
creating a fenestration in a host vein in the region of a malfunctioning valve, wherein the fenestration has a shape corresponding to a patch for a replacement valve; and
closing the fenestration after forming a monocusp venous valve using a patch of contiguous tissue,
wherein said patch is excised from a patch of contiguous xenogeneic heart valve tissue comprising the natural sinus, and wherein the patch of contiguous xenogeneic heart valve tissue comprising the natural sinus is configured so that the natural sinus provides a spatial buffer between a free edge of the noncoronary leaflet and a valve wall that facilitates opening and closing of the noncoronary leaflet based on flow pressure through the valve.