| CPC A61L 27/50 (2013.01) [A61F 2250/0082 (2013.01); A61L 2430/20 (2013.01)] | 19 Claims |

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15. A prosthetic heart valve, comprising:
a support structure; and
a valve assembly attached to the support structure, the valve assembly including a cuff and a plurality of prosthetic leaflets, each leaflet in the plurality of prosthetic leaflets being composed of a synthetic polymeric material and having an attachment edge attached to the support structure and a free edge, the plurality of prosthetic leaflets having a closed condition in which the plurality of prosthetic leaflets coapt to restrict blood from flowing in a retrograde direction through the support structure, and an open condition in which the plurality of prosthetic leaflets allow blood to flow in an antegrade direction through the support structure, the plurality of prosthetic leaflets not having a condition which purposefully enables blood to flow in the retrograde direction through the support structure,
wherein the synthetic material of one of the prosthetic leaflets in the plurality of prosthetic leaflets includes a first heat set fold or crease extending in an arcuate direction substantially matching a curvature of the attachment edge of the one prosthetic leaflet and a second heat set fold or crease extending only from the first fold or crease toward the free edge to assist the one prosthetic leaflet in transitioning between the closed condition and the open condition in a particular and repeatable desired movement.
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