US 12,329,861 B2
Transdermal drug delivery system and uses thereof
William Kazman, Westford, MA (US); Donald DeGolyer, Kiawah Island, SC (US); and Darren Leo Miller, Westford, MA (US)
Assigned to ATEGENOS PHARMACEUTICALS INC., Cambridge, MA (US)
Filed by Ategenos Pharmaceuticals Inc., Cambridge, MA (US)
Filed on May 24, 2024, as Appl. No. 18/674,321.
Application 18/674,321 is a continuation of application No. PCT/US2024/031005, filed on May 24, 2024.
Claims priority of provisional application 63/504,475, filed on May 26, 2023.
Prior Publication US 2024/0390288 A1, Nov. 28, 2024
Int. Cl. A61K 9/70 (2006.01); A61K 9/00 (2006.01); A61M 35/00 (2006.01); G16H 20/13 (2018.01); G16H 40/67 (2018.01)
CPC A61K 9/7038 (2013.01) [A61K 9/0009 (2013.01); A61M 35/10 (2019.05); G16H 20/13 (2018.01); G16H 40/67 (2018.01); A61M 2205/13 (2013.01); A61M 2205/14 (2013.01); A61M 2205/3306 (2013.01); A61M 2205/3327 (2013.01); A61M 2205/3576 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A transdermal drug delivery smart patch comprising, in and/or on the transdermal drug delivery smart patch:
a drug-containing layer;
a communication interface;
one or more sensors configured to detect a status change of the smart patch, the status change comprising one or more of (i) removing a packaging from the smart patch, (ii) removing a liner from an adhesive layer of the smart patch, (iii) applying the smart patch to the skin of the patient, or (iv) removing the smart patch from the skin of the patient; and
a processor communicatively coupled to the one or more sensors and the communication interface, wherein the processor is configured to perform operations comprising:
(a) automatically transiting between a plurality of working conditions based on the status change of the smart patch, wherein the plurality of working conditions of the smart patch comprises a hibernation mode, a sleep mode, and a work mode, and wherein the smart patch does not send out or receive communication signals in the hibernation mode, and
(b) transmitting smart patch status data using the communication interface.