	US 12,329,800 B2
	Annexin-coated particles
Peter Krammer, Heidelberg (DE); Heiko Weyd, Heidelberg (DE); and Kevin Bode, Heidelberg (DE)
Assigned to Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts, Heidelberg (DE)
Appl. No. 17/429,532
Filed by Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts, Heidelberg (DE)
PCT Filed Feb. 6, 2020, PCT No. PCT/EP2020/053007 § 371(c)(1), (2) Date Aug. 9, 2021, PCT Pub. No. WO2020/161247, PCT Pub. Date Aug. 13, 2020.
Claims priority of application No. 19156258 (EP), filed on Feb. 8, 2019.
Prior Publication US 2022/0152149 A1, May 19, 2022
Int. Cl. A61K 38/00 (2006.01); A61K 9/16 (2006.01); A61K 38/17 (2006.01); A61K 47/54 (2017.01); A61P 37/06 (2006.01)

CPC A61K 38/1709 (2013.01) [A61K 9/167 (2013.01); A61K 47/544 (2017.08); A61P 37/06 (2018.01)]

14 Claims

1. An annexin-coated particle, comprising a negatively charged phospholipid and annexin non-covalently coupled thereto, wherein the particle is a lipid vesicle; and the annexin is a receptor-binding annexin core domain.