US 12,329,796 B2
Anti-obesity composition
Yong Wook Lee, Gyeonggi-do (KR); Chan Sung Park, Seoul (KR); Joo Hyun Oh, Gyeonggi-do (KR); Ji Min Kim, Gyeonggi-do (KR); and Ha Neul Jo, Gyeonggi-do (KR)
Assigned to NATURAL ENDOTECH CO., LTD., Gyeonggi-do (KR)
Appl. No. 18/008,219
Filed by NATURAL ENDOTECH CO., LTD., Gyeonggi-do (KR)
PCT Filed May 24, 2021, PCT No. PCT/KR2021/006436
§ 371(c)(1), (2) Date Dec. 5, 2022,
PCT Pub. No. WO2021/246703, PCT Pub. Date Dec. 9, 2021.
Claims priority of application No. 10-2020-0068218 (KR), filed on Jun. 5, 2020.
Prior Publication US 2023/0201289 A1, Jun. 29, 2023
Int. Cl. A61K 36/27 (2006.01); A61K 9/00 (2006.01); A61K 36/232 (2006.01); A61K 36/53 (2006.01); A61P 3/04 (2006.01)
CPC A61K 36/27 (2013.01) [A61K 9/0056 (2013.01); A61K 36/232 (2013.01); A61K 36/53 (2013.01); A61P 3/04 (2018.01); A61K 2236/333 (2013.01)] 3 Claims
 
1. A method for prevention, treatment or alleviation of obesity comprising:
administering, to a subject, a composition comprising an initial crude extract obtained by extraction with a solvent consisting of water from a combination consisting of Cynanchi Wilfordii Radix, Phlomis umbrosa TURCZ, and angelica,
wherein the extract reduces blood triglyceride levels and regulates expression of PPARγ and GLUT4 proteins.