US 12,329,653 B2
Porous spinal fusion implant
Jesse Unger, San Diego, CA (US); Jeremy Malik, San Diego, CA (US); and Ryan Donahoe, San Diego, CA (US)
Assigned to Nuvasive Inc., San Diego, CA (US)
Filed by NuVasive, Inc., San Diego, CA (US)
Filed on Apr. 10, 2023, as Appl. No. 18/297,747.
Application 18/297,747 is a continuation of application No. 16/866,713, filed on May 5, 2020, granted, now 11,660,203.
Application 16/866,713 is a continuation of application No. 16/010,405, filed on Jun. 16, 2018, granted, now 10,675,158, issued on Jun. 9, 2020.
Application 16/010,405 is a continuation of application No. PCT/US2016/067371, filed on Dec. 16, 2016.
Claims priority of provisional application 62/379,988, filed on Aug. 26, 2016.
Claims priority of provisional application 62/354,077, filed on Jun. 23, 2016.
Claims priority of provisional application 62/268,430, filed on Dec. 16, 2015.
Prior Publication US 2023/0240858 A1, Aug. 3, 2023
Int. Cl. A61F 2/44 (2006.01); A61F 2/30 (2006.01)
CPC A61F 2/4455 (2013.01) [A61F 2/30771 (2013.01); A61F 2/44 (2013.01); A61F 2002/30011 (2013.01); A61F 2002/30014 (2013.01); A61F 2002/3008 (2013.01); A61F 2002/30593 (2013.01); A61F 2002/30784 (2013.01); A61F 2002/30787 (2013.01); A61F 2002/30838 (2013.01); A61F 2002/30891 (2013.01); A61F 2002/3092 (2013.01); A61F 2002/3093 (2013.01); A61F 2002/30985 (2013.01); A61F 2002/4495 (2013.01); A61F 2310/00592 (2013.01)] 14 Claims
OG exemplary drawing
 
1. A system comprising:
an implant configured to engage a spine, wherein the implant comprises:
a first endplate including a first microporous bone contacting surface defined by a plurality of struts forming a plurality of irregularly shaped micropores having a first average pore size,
a second endplate including a second microporous bone contacting surface defined by a plurality of struts forming a plurality of irregularly shaped micropores having a second average pore size, and
a porous body positioned between the first endplate and the second endplate, wherein the porous body comprises a macroporous lattice structure defined by a plurality of struts forming a plurality of non-uniform, irregularly shaped, non-polygonal macropores having a third average pore size,
a fusion aperture extending through the first endplate, the second endplate, and the porous body, and
a frame positioned along an inner perimeter of the first endplate and an inner perimeter of the second endplate, wherein the inner perimeters of the first and second endplates laterally surround the fusion aperture;
and
a fixation element configured to couple the implant to the spine,
wherein the first endplate comprises a porous density that varies along a vertical extent thereof, and wherein the porous density at the first microporous bone contacting surface differs from that of a microporous body contacting bottom surface thereof,
wherein each one of the plurality of struts of the first endplate, the second endplate, and the porous body are non-planar and have an irregular pattern,
wherein a thickness of each one of the plurality of struts of the first endplate, the second endplate, and the porous body is greater at an end of the strut than in a middle of the strut, and wherein a minimum and maximum thickness of each strut vary from strut to strut,
wherein the plurality of struts and plurality of irregularly shaped pores are smaller in the first endplate and the second endplate than in the porous body, and
wherein the first microporous bone contacting surface and the second microporous bone contacting surface each have regions of different elastic modulus.