US 12,329,527 B2
Method and device for detecting a neural response in neural measurements
John Louis Parker, Artarmon (AU); and Milan Obradovic, Artarmon (AU)
Assigned to Saluda Medical Pty Ltd, Macquarie Park (AU)
Filed by Saluda Medical Pty Ltd, Artarmon (AU)
Filed on Apr. 6, 2021, as Appl. No. 17/223,498.
Application 17/223,498 is a continuation of application No. 15/527,314, granted, now 11,006,846, previously published as PCT/AU2015/050724, filed on Nov. 17, 2015.
Claims priority of application No. 2014904595 (AU), filed on Nov. 17, 2014.
Prior Publication US 2021/0267518 A1, Sep. 2, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 5/24 (2021.01); A61B 5/00 (2006.01); A61B 5/316 (2021.01); A61B 5/388 (2021.01); A61B 5/389 (2021.01); A61N 1/36 (2006.01); G16H 40/63 (2018.01)
CPC A61B 5/24 (2021.01) [A61B 5/316 (2021.01); A61B 5/388 (2021.01); A61B 5/407 (2013.01); A61B 5/7203 (2013.01); A61B 5/7214 (2013.01); A61B 5/7282 (2013.01); G16H 40/63 (2018.01); A61B 5/389 (2021.01); A61B 5/4836 (2013.01); A61N 1/36135 (2013.01)] 23 Claims
OG exemplary drawing
 
1. A method for detecting locally evoked neural responses in neural measurements obtained in the presence of distally evoked neural responses, the method comprising:
applying, by an implantable device, an electrical stimulus to a neural pathway;
obtaining, by the implantable device, a first neural measurement from a first sense electrode coupled to the implantable device;
obtaining, by the implantable device, a contemporaneous second neural measurement from a second sense electrode coupled to the implantable device and spaced apart from the first electrode along the neural pathway;
determining, by the implantable device, a neural response decay, the neural response decay being a measure of decay in a neural response from the first sense electrode to the second sense electrode, from the first neural measurement and the second neural measurement;
determining, by the implantable device, from the neural response decay whether a locally evoked neural response is present in the neural measurements; and
applying, by the implantable device, neurostimulation in response to the determining from the neural response decay whether a locally evoked neural response is present in the neural measurements.