| CPC A61B 5/1106 (2013.01) [A61B 3/113 (2013.01); A61B 5/0004 (2013.01); A61B 5/1101 (2013.01); A61B 5/1103 (2013.01); A61B 5/1126 (2013.01); A61B 5/4064 (2013.01); A61B 5/6821 (2013.01); A61B 5/68335 (2017.08); A61B 5/742 (2013.01); A61B 5/002 (2013.01); A61B 2562/0261 (2013.01); A61B 2562/164 (2013.01); A61B 2562/222 (2013.01); A61B 2562/227 (2013.01)] | 20 Claims |

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1. An apparatus comprising:
a sensor comprising:
a sensing element comprising:
a first piezoelectric element and a second piezoelectric element; and
at least one electrically conductive surface electrically coupled with the first or the second piezoelectric element; and
an amplifier comprising a receptacle electrically coupled with the at least one electrically conductive surface;
wherein the sensor is configured to conform to a shape of an eye and operate within a fold of an eyelid of a patient and to register micro-movements of an eyeball having an amplitude in an inclusive range of 40 micrometers to 500 nanometers; and
wherein sensor is configured for placement with the eyelid of the patient disposed between the sensor and the eyeball.
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