| CPC A61B 17/0057 (2013.01) [A61B 17/0401 (2013.01); A61B 17/12109 (2013.01); A61B 2017/00349 (2013.01); A61B 2017/00575 (2013.01); A61B 2017/0065 (2013.01); A61B 2017/00663 (2013.01); A61B 2017/00668 (2013.01); A61B 2017/00672 (2013.01); A61B 2017/00676 (2013.01); A61B 2017/00778 (2013.01); A61B 2017/00862 (2013.01); A61B 2017/00867 (2013.01); A61B 2017/0409 (2013.01); A61B 2017/0427 (2013.01); A61B 2017/0619 (2013.01); A61B 2017/12004 (2013.01); A61B 17/12013 (2013.01); A61B 17/1227 (2013.01); A61B 2017/2906 (2013.01)] | 16 Claims |

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1. A method for vascular closure, comprising:
disposing a distal end of a housing of a vascular closure device to a position above and adjacent a passage in a tissue layer while the tissue layer is disposed above and adjacent an access hole in a wall of a blood vessel;
deploying a plurality of anchor deployers from a distal section of the housing by distally advancing deployment rods of the anchor deployers in a distal and radially outward direction from the housing into the tissue layer in positions disposed about the passage in the tissue layer;
securing respective anchors of the anchor deployers to the tissue layer in the positions disposed about the passage in the tissue layer;
proximally retracting the deployment rods back into the distal section of the housing so as to draw the anchors and respective tissue layer portions secured thereto together adjacent the distal section of the housing thereby closing the passage in the tissue layer and achieving a tissue lock indirectly sealing the access hole in the blood vessel while the tissue layer is disposed above and adjacent the access hole in the wall of the blood vessel;
deploying a tissue grip over the anchors and onto the tissue layer portions secured to the anchors so as to secure the tissue layer portions together; and
actuating the anchors to release them from the tissue layer portions prior to withdrawal of the anchors into the distal section of the housing.
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