US 12,006,527 B2
Coryneform bacterium transformant and method for producing 2-phenylethanol using same
Masayuki Inui, Kyoto (JP); Kazumi Hiraga, Kyoto (JP); Masako Suda, Kyoto (JP); Masayoshi Hashizume, Tokyo (JP); and Junya Ishida, Tokyo (JP)
Assigned to Research Institute of Innovative Technology for the Earth, Kyoto (JP); and Sumitomo Bakelite Co., Ltd., Tokyo (JP)
Appl. No. 17/414,021
Filed by Research Institute of Innovative Technology for the Earth, Kyoto (JP); and Sumitomo Bakelite Co., Ltd., Tokyo (JP)
PCT Filed Dec. 19, 2019, PCT No. PCT/JP2019/049921
§ 371(c)(1), (2) Date Jun. 15, 2021,
PCT Pub. No. WO2020/130095, PCT Pub. Date Jun. 25, 2020.
Claims priority of application No. 2018-238497 (JP), filed on Dec. 20, 2018.
Prior Publication US 2022/0025412 A1, Jan. 27, 2022
Int. Cl. C12P 7/22 (2006.01); C12N 15/77 (2006.01); C12R 1/15 (2006.01)
CPC C12P 7/22 (2013.01) [C12N 15/77 (2013.01); C12R 2001/15 (2021.05)] 23 Claims
 
1. A coryneform bacterium transformant selected from the group consisting of:
(a) a Corynebacterium glutamicum transformant obtained by introducing a gene that encodes an enzyme having phenylpyruvate decarboxylase activity into a Corynebacterium glutanicum in such a manner that the gene can be expressed, wherein the gene that encodes an enzyme having phenylpyruvate decarboxylase activity is a gene comprising a sequence having at least 98% identity to SEQ ID NO: 2;
(b) a coryneform bacterium transformant obtained by introducing a plasmid having a gene that encodes an enzyme having phenylpyruvate decarboxylase activity into a coryneform bacterium in such a manner that the gene can be expressed, wherein the gene that encodes an enzyme having phenylpyruvate decarboxylase activity is a gene comprising a sequence having at least 98% identity to SEQ ID NO: 2; and
(c) a coryneform bacterium transformant obtained by introducing a gene that encodes an enzyme having phenylpyruvate decarboxylase activity into a coryneform bacterium in such a manner that the gene can be expressed, wherein the gene that encodes an enzyme having phenylpyruvate decarboxylase activity is a gene comprising the sequence of SEQ ID NO:3.