CPC C07D 487/04 (2013.01) | 21 Claims |
1. A compound of Formula (I):
![]() or a pharmaceutically acceptable salt, stereoisomer, or tautomer thereof,
wherein:
R1 is H, halogen, CN, alkyl, C(O)N(R7)2, C(O)OH, C(O)OR6, NH2, O(alkyl), O(phenyl), or aryl, wherein the alkyl is optionally substituted with one or more substituents independently selected from the group consisting of OH and O(alkyl);
R2 is H, halogen, CN, alkyl, C(O)N(R7)2, C(O)OH, C(O)OR6, NH2, O(alkyl), O(phenyl), or aryl, wherein the alkyl is optionally substituted with one or more substituents independently selected from the group consisting of OH and O(alkyl);
R3 is alkyl;
R4 is alkyl, haloalkyl, or cycloalkyl;
R5 is C(O)N(R9)2, C(O)OH, or C(O)OR8;
each R6 is independently H, alkyl, haloalkyl, NH2, O(alkyl), O(haloalkyl), cycloalkyl, heterocycloalkyl, phenyl, or 5- or 6-membered heteroaryl;
each R7 is independently H, alkyl, haloalkyl, NH2, O(alkyl), O(haloalkyl), cycloalkyl, heterocycloalkyl, phenyl, or 5- or 6-membered heteroaryl;
R8 is H, alkyl, haloalkyl, NH2, O(alkyl), O(haloalkyl), cycloalkyl, heterocycloalkyl, phenyl, or 5- or 6-membered heteroaryl; and
each R9 is independently H, alkyl, haloalkyl, NH2, O(alkyl), O(haloalkyl), cycloalkyl, heterocycloalkyl, phenyl, or 5- or 6-membered heteroaryl.
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