US 12,005,447 B2
Apparatus and method for bio-particle detection
Won Jong Jung, Seoul (KR); Hyeong Seok Jang, Seoul (KR); Kak Namkoong, Seoul (KR); Hyung Jun Youn, Suwon-si (KR); and Jae Hong Lee, Suwon-si (KR)
Assigned to SAMSUNG ELECTRONICS CO., LTD., Suwon-si (KR)
Filed by SAMSUNG ELECTRONICS CO., LTD., Suwon-si (KR)
Filed on Aug. 16, 2022, as Appl. No. 17/889,085.
Claims priority of application No. 10-2022-0035899 (KR), filed on Mar. 23, 2022.
Prior Publication US 2023/0302447 A1, Sep. 28, 2023
Int. Cl. B01L 7/00 (2006.01); B01L 3/00 (2006.01); G01N 15/06 (2006.01); G01N 15/01 (2024.01); G01N 15/075 (2024.01)
CPC B01L 3/502715 (2013.01) [B01L 7/52 (2013.01); G01N 15/06 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/1822 (2013.01); B01L 2300/1894 (2013.01); G01N 15/01 (2024.01); G01N 15/075 (2024.01)] 20 Claims
OG exemplary drawing
 
1. An apparatus for bio-particle detection, the apparatus comprising:
a bio-particle detection chip comprising a substrate having a plurality of through-hole groups, each through-hole group of the plurality of through-hole groups including through-holes which pass through the substrate from a first surface of the substrate toward an second surface of the substrate opposite to the first surface, and which are configured to accommodate a sample solution loaded therein; and
a processor configured to determine a number of through-holes, among the through holes of at least one through-hole group of the plurality of through-hole groups, having a target material encapsulated therein, based on at least one of an electrical signal and an optical signal corresponding to the through-holes of the at least one through-hole group, and to estimate a concentration of the target material based on the determined number;
wherein the through-holes of each of the plurality of through-hole groups have at least one of diameters, volumes, shapes, or arrangement interval different than respective diameters, volumes, shapes, or arrangement interval of the through-holes of other through-hole groups of the plurality of through-hole groups.