	US 12,005,076 B2
	Zinc phosphate complex
Baohua Qiao, Howell, NJ (US); Long Pan, Somerset, NJ (US); Gregory Szewczyk, Flemington, NJ (US); and Ravi Subramanyam, Belle Mead, NJ (US)
Assigned to Colgate-Palmolive Company, New York, NY (US)
Appl. No. 15/538,330
Filed by Colgate-Palmolive Company, New York, NY (US)
PCT Filed Dec. 26, 2014, PCT No. PCT/US2014/072420 § 371(c)(1), (2) Date Jun. 21, 2017, PCT Pub. No. WO2016/105429, PCT Pub. Date Jun. 30, 2016.
Prior Publication US 2017/0348352 A1, Dec. 7, 2017
Int. Cl. A61K 33/42 (2006.01); A61K 6/20 (2020.01); A61K 6/74 (2020.01); A61K 8/24 (2006.01); A61K 8/27 (2006.01); A61K 9/00 (2006.01); A61K 33/30 (2006.01); A61Q 11/00 (2006.01); A61Q 15/00 (2006.01); C01B 25/37 (2006.01)

CPC A61K 33/42 (2013.01) [A61K 6/20 (2020.01); A61K 6/74 (2020.01); A61K 8/24 (2013.01); A61K 8/27 (2013.01); A61K 9/0063 (2013.01); A61K 33/30 (2013.01); A61Q 11/00 (2013.01); A61Q 15/00 (2013.01); C01B 25/37 (2013.01); A61K 2800/262 (2013.01); A61K 2800/58 (2013.01)]

4 Claims

1. A soluble zinc polyphosphate complex in solution, wherein the complex is obtainable by combining ingredients consisting of zinc chloride and sodium hexametaphosphate in an aqueous solvent;

wherein the zinc polyphosphate complex in solution consists of zinc and a polyphosphate chain, wherein the phosphorus to zinc mole ratio of the zinc polyphosphate complex is 20:1; and

wherein upon contact with proteins in saliva in an oral cavity, the soluble zinc polyphosphate complex forms a precipitate which occludes dentinal tubules.