US 12,005,070 B2
Protective agent for keratoconjunctiva or suppressive agent for keratoconjunctival disorder
Kyo Aizawa, Chiba (JP); Yoshihisa Iida, Tokyo (JP); Takashi Shimoida, Tokyo (JP); Yasuhiro Kotani, Tokyo (JP); Koushi Iwata, Tokushima (JP); and Kazuhisa Doi, Tokushima (JP)
Assigned to TOYO SUGAR REFINING CO., LTD., Tokyo (JP); and OTSUKA PHARMACEUTICAL FACTORY, INC., Naruto (JP)
Filed by TOYO SUGAR REFINING CO., LTD., Tokyo (JP); and OTSUKA PHARMACEUTICAL FACTORY, INC., Tokushima (JP)
Filed on Sep. 1, 2016, as Appl. No. 15/254,655.
Application 15/254,655 is a division of application No. 14/360,070, abandoned, previously published as PCT/JP2012/083039, filed on Nov. 22, 2012.
Claims priority of application No. 2011-256516 (JP), filed on Nov. 24, 2011.
Prior Publication US 2016/0367584 A1, Dec. 22, 2016
Int. Cl. A61K 31/7032 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01)
CPC A61K 31/7032 (2013.01) [A61K 9/0048 (2013.01); A61K 9/08 (2013.01)] 4 Claims
 
1. A method of protecting keratoconjunctiva from dry eye in a subject, the method comprising: administering to the subject's eye an ophthalmic formulation comprising an effective amount of glucosylglycerol and an ophthalmically acceptable carrier, wherein the glucosylglycerol is present in an amount of from 0.01 to 10% by mass of the ophthalmic formulation.