CPC A61K 31/439 (2013.01) [A61K 9/28 (2013.01); A61K 9/48 (2013.01); A61K 31/43 (2013.01); A61K 31/4439 (2013.01); A61P 31/04 (2018.01)] | 14 Claims |
1. A method for treating, ameliorating, and/or reversing a Helicobacter pylori (H. pylori) infection in a patient in need thereof, comprising administering to said patient:
an effective amount of compound I 4-Deoxy-3,4-(1H)-imidazo-(2,5-dihydro)rifamycin, or a pharmaceutically acceptable salt thereof; an effective amount of an additional antibiotic, and an effective amount of an acid blocker,
wherein said compound I is administered to said patient at a dose of about 400 mg to about 600 mg, twice per day (BID) or three times per day (TID),
wherein said compound I is a compound of Formula 2
![]() wherein an effective amount of said acid blocker is at a dose of about 10 mg to about 20 mg, and said acid blocker is proton pump inhibitor (PPI); and,
wherein an effective amount of said additional antibiotic is twice per day (BID) or three times per day (TID), for 7-14 consecutive days; and said additional antibiotic is amoxicillin.
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