	US 12,005,049 B2
	Methods of preventing cancer metastasis
Kazuko Matsuda, La Jolla, CA (US); Grazia Ambrosini, Astoria, NY (US); Gary K. Schwartz, Briarcliff Manor, NY (US); and Alex J. Rai, Montclair, NJ (US)
Assigned to MediciNova, Inc., La Jolla, CA (US); and The Trustees of Columbia University in the City of New York, New York, NY (US)
Filed by MediciNova, Inc., La Jolla, CA (US); and The Trustees of Columbia University in the City of New York, New York, NY (US)
Filed on Jul. 25, 2022, as Appl. No. 17/872,855.
Claims priority of provisional application 63/225,820, filed on Jul. 26, 2021.
Prior Publication US 2023/0037014 A1, Feb. 2, 2023
Int. Cl. A61K 31/437 (2006.01); A61P 35/00 (2006.01)

CPC A61K 31/437 (2013.01) [A61P 35/00 (2018.01)]

16 Claims

1. A method of preventing, ameliorating, or minimizing metastasis of eye cancer in a patient in need thereof, the method comprising:

administering to the patient a therapeutically effective amount of ibudilast, or a pharmaceutically acceptable salt thereof.