US 12,005,033 B2
Compositions comprising mixtures of semifluorinated alkanes
Bernhard Günther, Dossenheim (DE); Bastian Theisinger, Mannheim (DE); Sonja Theisinger, Mannheim (DE); and Dieter Scherer, Laufen (CH)
Assigned to NOVALIQ GMBH, Heidelberg (DE)
Filed by Novaliq GmbH, Heidelberg (DE)
Filed on Sep. 20, 2019, as Appl. No. 16/578,080.
Application 16/578,080 is a continuation of application No. 14/427,927, granted, now 10,449,164, previously published as PCT/EP2013/068882, filed on Sep. 12, 2013.
Claims priority of application No. 12183997 (EP), filed on Sep. 12, 2012.
Prior Publication US 2020/0188318 A1, Jun. 18, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/02 (2006.01); A61K 9/00 (2006.01); A61K 47/06 (2006.01)
CPC A61K 31/02 (2013.01) [A61K 9/0048 (2013.01); A61K 47/06 (2013.01)] 24 Claims
 
1. A method for the treatment of a disease or disorder selected from keratoconjunctivitis sicca, Sjogren syndrome, lacrimal gland insufficiency, meibomian gland disease, and/or meibomian gland dysfunction, comprising administering to a patient in need thereof a composition comprising:
one semifluorinated alkane or two or more different semifluorinated alkanes, wherein said composition is free of a therapeutically effective amount of any pharmaceutically active drug substance useful for ophthalmic treatment
wherein the composition is topically administered to an eye or ophthalmic tissue.