US 12,327,649 B2
Production of radioisotopes
Jan Rijn Zeevaart, Pretoria (ZA)
Assigned to The South African Nuclear Energy Corporation SOC Limited, North West Province (ZA)
Appl. No. 16/623,333
Filed by The South African Nuclear Energy Corporation SOC Limited, North West Province (ZA)
PCT Filed Jun. 29, 2018, PCT No. PCT/IB2018/054858
§ 371(c)(1), (2) Date Dec. 16, 2019,
PCT Pub. No. WO2019/003202, PCT Pub. Date Jan. 3, 2019.
Claims priority of application No. 2017/04408 (ZA), filed on Jun. 29, 2017.
Prior Publication US 2020/0312476 A1, Oct. 1, 2020
Int. Cl. G21G 1/00 (2006.01); A61K 51/00 (2006.01); A61N 5/10 (2006.01); G21G 1/12 (2006.01)
CPC G21G 1/12 (2013.01) [A61K 51/00 (2013.01); A61N 5/1001 (2013.01); A61N 2005/1019 (2013.01); A61N 2005/1089 (2013.01); G21G 2001/0036 (2013.01)] 9 Claims
OG exemplary drawing
 
1. A method of producing a radioisotope of a target element (“target element radioisotope”), the method including:
irradiating a target compound, comprising the target element, with gamma radiation, as high energy photon irradiation, in a radiation therapy device, wherein the irradiation is performed upstream of a gamma radiation generation target of the radiation therapy device and wherein the gamma radiation is produced as high energy photon irradiation by irradiating a gamma radiation source element or compound with electron beam radiation of an electron beam that is produced by the radiation therapy device, thereby producing the target element radioisotope,
wherein the target element radioisotope is a radioisotope of the target element and is of an oxidation state different than that of the target element and is comprised in a target element radioisotope compound that is different from the target compound and that is separable from the target compound by a physical and/or chemical separation method; and
wherein the target compound is in gaseous form and is contained in a target compound chamber defined by a module of the radiation therapy device, which module is located in the path of the electron beam upstream of the gamma radiation generation target of the radiation therapy device, and which module contains, in addition to the target compound, the gamma radiation source element or compound.