US 12,327,615 B2
Genetic comparisons between grandparents and grandchildren
Linda Avey, Lafayette, CA (US); Oleksiy Khomenko, Stanford, CA (US); Brian Thomas Naughton, Mountain View, CA (US); Serge Saxonov, Oakland, CA (US); Anne Wojcicki, Palo Alto, CA (US); and Alexander Wong, Palo Alto, CA (US)
Assigned to 23andMe, Inc., Sunnyvale, CA (US)
Filed by 23andMe, Inc., Sunnyvale, CA (US)
Filed on Sep. 27, 2021, as Appl. No. 17/449,081.
Application 17/449,081 is a continuation of application No. 15/829,782, filed on Dec. 1, 2017, granted, now 11,170,873.
Application 15/829,782 is a continuation of application No. 12/288,026, filed on Oct. 15, 2008, granted, now 9,864,835, issued on Jan. 9, 2018.
Claims priority of provisional application 60/999,065, filed on Oct. 15, 2007.
Prior Publication US 2022/0157405 A1, May 19, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. G16B 45/00 (2019.01); G16B 10/00 (2019.01); G16B 20/00 (2019.01); G16B 20/20 (2019.01); G16B 20/40 (2019.01); G16B 30/00 (2019.01)
CPC G16B 45/00 (2019.02) [G16B 20/20 (2019.02); G16B 20/40 (2019.02); G16B 10/00 (2019.02); G16B 20/00 (2019.02); G16B 30/00 (2019.02)] 42 Claims
 
1. A computer-implemented method for graphically displaying a first estimated amount of genotypic information inherited by a first grandchild from a first grandparent of the first grandchild using a user interface to receive user input and interact with a system or a genome database comprising genotypic information of the first grandchild and the first grandparent, the first grandchild being biologically related to the first grandparent, the method comprising:
(a) causing to be displayed on a display device of a computer system:
a graphical tree structure comprising:
a first grandparent position corresponding to genotypic information of the first grandparent;
a first grandchild position corresponding to genotypic information of the first grandchild;
a first graphically displayed box and/or line for graphically displaying an indication of genotypic information of the first grandparent; and
a second graphically displayed box and/or line configured to be updated to graphically display the first estimated amount of genotypic information inherited by the first grandchild from the first grandparent;
wherein the first and second graphically displayed boxes and/or lines are positioned with respect to one another in the graphical tree structure in a manner depicting a relationship between the first grandchild and the first grandparent;
(b) receiving a user-specified indication of the first grandparent;
(c) receiving a user-specified indication of the first grandchild;
(d) sending to the system or the genome database the user-specified indications of (b) and (c) for each of the first grandchild and the first grandparent;
(e) receiving from the system or the genome database the first estimated amount of genotypic information inherited by the first grandchild from the first grandparent, wherein the first estimated amount is based at least in part on the genotypic information of the first grandparent and the genotypic information of the first grandchild; and
(f) based on the first estimated amount received in (e), causing to be automatically updated the graphical tree structure displayed on the display device, wherein the causing to be automatically updated is performed by a processor configured to update the graphical tree structure, wherein causing to be automatically updated includes causing updating of the second graphically displayed box and/or line to display a graphical indication of the first estimated amount of genotypic information inherited by the first grandchild from the first grandparent, wherein the second graphically displayed box and/or line is updated to be proportional to the first estimated amount of genotypic information inherited by the first grandchild from the first grandparent.