US 12,326,442 B2
Device with a fluid component assessment feature
Jennifer Samproni, Braintree, MA (US); Manish Deshpande, Newton, MA (US); and Peter Paulicka, Röttenbach (DE)
Assigned to Siemens Healthcare Diagnostics Inc., Tarrytown, NY (US)
Appl. No. 17/299,821
Filed by Siemens Healthcare Diagnostics Inc., Tarrytown, NY (US)
PCT Filed Dec. 5, 2019, PCT No. PCT/US2019/064627
§ 371(c)(1), (2) Date Jun. 4, 2021,
PCT Pub. No. WO2020/118021, PCT Pub. Date Jun. 11, 2020.
Claims priority of provisional application 62/776,825, filed on Dec. 7, 2018.
Prior Publication US 2022/0023857 A1, Jan. 27, 2022
Int. Cl. G01N 33/49 (2006.01); B01L 3/00 (2006.01); G01N 21/25 (2006.01); G01N 21/77 (2006.01)
CPC G01N 33/491 (2013.01) [B01L 3/508 (2013.01); G01N 21/251 (2013.01); G01N 21/77 (2013.01); G01N 33/4915 (2013.01); G01N 33/4925 (2013.01); B01L 2200/0689 (2013.01); B01L 2200/16 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/0681 (2013.01); B01L 2400/0478 (2013.01); G01N 2021/7763 (2013.01); G01N 2201/0221 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A device, comprising:
a housing constructed of a fluid impermeable material and defining a first fluid port and a second fluid port, the first fluid port configured to connect to a fluid collection device to form a fluid tight seal upon the first fluid port being connected to the fluid collection device, the first fluid port configured to receive a fluid sample from the fluid collection device into the housing, wherein the fluid sample is blood having red blood cells and plasma, and the second fluid port is configured to pass the fluid sample from the housing into an external testing instrument;
a zone formed in the housing, the zone constructed of a material that allows an analysis of the fluid sample positioned within the housing and located adjacent to the zone, the zone being an optical zone constructed of a material that is transparent to visible light; and
a lateral flow membrane configured to separate the red blood cells from the plasma to present plasma substantially devoid of red blood cells within the optical zone.