US 12,325,850 B2
Microrobot-based biomimetic system
Hong Soo Choi, Daegu (KR); Jin Young Kim, Gyeonggi-do (KR); Seung Min Lee, Gyeongsangbuk-do (KR); and Sang Won Kim, Daegu (KR)
Assigned to Daegu Gyeongbuk Institute of Science and Technology, Daegu (KR)
Appl. No. 16/312,757
Filed by Daegu Gyeongbuk Institute of Science and Technology, Daegu (KR)
PCT Filed Jun. 22, 2017, PCT No. PCT/KR2017/006590
§ 371(c)(1), (2) Date Dec. 21, 2018,
PCT Pub. No. WO2017/222321, PCT Pub. Date Dec. 28, 2017.
Claims priority of application No. 10-2016-0077807 (KR), filed on Jun. 22, 2016; application No. 10-2016-0077809 (KR), filed on Jun. 22, 2016; and application No. 10-2016-0077813 (KR), filed on Jun. 22, 2016.
Prior Publication US 2019/0359928 A1, Nov. 28, 2019
Int. Cl. B01L 3/00 (2006.01); A61B 1/04 (2006.01); C12M 1/00 (2006.01); C12M 1/34 (2006.01); C12M 1/42 (2006.01); C12M 3/00 (2006.01); C12M 3/06 (2006.01)
CPC C12M 35/08 (2013.01) [A61B 1/04 (2013.01); B01L 3/50273 (2013.01); C12M 21/08 (2013.01); C12M 23/16 (2013.01); C12M 29/00 (2013.01); C12M 41/00 (2013.01); B01L 2200/143 (2013.01); B01L 2300/12 (2013.01); B01L 2300/16 (2013.01); B01L 2400/043 (2013.01)] 6 Claims
OG exemplary drawing
 
1. A microrobot-based biometric system comprising:
a plurality of chambers configured to contain microorgans, respectively, the microorgans comprising a target microorgan and a non-target microorgan;
a channel connecting the plurality of chambers that are disposed on a same surface as the channel;
at least one microrobot configured to move along the channel to perform target-directed delivery of a drug or cell; and
a magnetic field controller configured to control operation of the at least one microrobot, and comprising:
at least one global magnetic field controller configured to apply an external magnetic field to an entire area of the biometric system; and
a plurality of local magnetic field controllers configured to individually apply a local magnetic field to the plurality of chambers,
wherein when the at least one microrobot reaches an area of the non-target microorgan, a local magnetic field controller arranged in the area of the non-target microorgan, among the plurality of local magnetic field controllers, controls a plurality of micro-coils included in the local magnetic field controller to stop the plurality of micro-coils from generating the local magnetic field, and the least one global magnetic field controller controls a plurality of micro-coils included in the least one global magnetic field controller to continue to generate the external magnetic field to cause the at least one microrobot to bypass the area of the non-target microorgan,
the at least one microrobot comprises a first microrobot that comprises a cap configured to load the drug or cell and a plunger connected to the cap, and
when the first microrobot reaches the target microorgan, a local magnetic field controller arranged in an area of the target microorgan, among the plurality of local magnetic field controllers, applies a rotating magnetic field to the first microrobot to cause the plunger of the first microrobot to rotate and to cause the first microrobot to release the drug or cell from the cap.