| CPC A61N 1/3712 (2013.01) | 19 Claims |

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1. A system comprising:
stimulation circuitry configured to generate a pacing stimulus;
sensing circuitry configured to sense an evoked response after the pacing stimulus, wherein the evoked response is indicative of capture of heart muscle in response to the pacing stimulus; and
processing circuitry configured to:
determine classification features from the evoked response;
apply the classification features to a classification model, the classification model generated by a machine learning algorithm using one or more test sets comprising a plurality of sample evoked responses for each of a plurality of classifications, wherein the plurality of classifications includes a selective capture, non-selective capture, and right ventricular capture;
based on the output of the model, classify the evoke response as a non-selective capture classification as a change from a selective capture classification for a previous evoked response; and
in response to determining the evoked response includes the change from the selective capture classification to the non-selective capture classification, change an amplitude level of pacing stimulus based on an amplitude level of the pacing stimulus causing an evoked response including a selective capture classification.
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