US 12,324,871 B2
Absorbable iron-based alloy implanted medical device and manufacturing method thereof
Haiping Qi, Shenzhen (CN); and Wenjiao Lin, Shenzhen (CN)
Assigned to BIOTYX MEDICAL (SHENZHEN) CO., LTD., Shenzhen (CN)
Appl. No. 15/776,514
Filed by Lifetech Scientific (Shenzhen) Co., Ltd., Shenzhen (CN)
PCT Filed Jun. 8, 2016, PCT No. PCT/CN2016/085187
§ 371(c)(1), (2) Date May 16, 2018,
PCT Pub. No. WO2017/084314, PCT Pub. Date May 26, 2017.
Claims priority of application No. 201510799593.7 (CN), filed on Nov. 18, 2015.
Prior Publication US 2018/0326128 A1, Nov. 15, 2018
Int. Cl. A61L 31/02 (2006.01); A61F 2/82 (2013.01); A61L 27/04 (2006.01); A61L 31/10 (2006.01); A61L 31/14 (2006.01)
CPC A61L 31/148 (2013.01) [A61F 2/82 (2013.01); A61L 27/04 (2013.01); A61L 31/022 (2013.01); A61L 31/10 (2013.01); A61F 2210/0004 (2013.01); A61F 2210/0076 (2013.01); A61F 2250/0067 (2013.01); A61L 2400/18 (2013.01)] 14 Claims
OG exemplary drawing
 
1. An absorbable iron-based alloy stent, comprising an iron-based alloy substrate having a surface, an alkaline protector disposed on the surface of the iron-based alloy substrate and having a surface, and a degradable polymer disposed on the surface of the alkaline protector, and wherein the alkaline protector comprises at least one alkaline substance; and the alkaline substance is selected from the group consisting of sodium hydroxide, zinc hydroxide, zinc oxide, sodium carbonate, sodium bicarbonate, potassium carbonate, potassium bicarbonate, sodium phosphate, sodium hydrogen phosphate, potassium phosphate, potassium hydrogen phosphate, sodium pyrophosphate, trisodium monohydrogen diphosphate, potassium pyrophosphate, tripotassium monohydrogen diphosphate, sodium polyphosphate, potassium polyphosphate, ammonium polyphosphate, sodium borate, potassium borate, calcium borate, sodium oxalate, potassium oxalate, calcium oxalate, trisodium citrate, sodium dihydrogen citrate, tripotassium citrate, potassium dihydrogen citrate, calcium citrate, calcium hydrogen citrate, sodium tartrate, potassium tartrate, calcium tartrate, ethylene diamine tetraacetic acid tetrasodium, ethylene diamine tetraacetic acid tetrapotassium, ethylene diamine tetraacetic acid calcium, sodium ethoxide, potassium ethoxide, calcium ethoxide, urea and hexamine; and
wherein the thickness of the alkaline protector is 6 μM, the thickness of the polymer is 8 μM, and the mass of the iron-based alloy substrate is 4.5-5 mg; or wherein the thickness of the alkaline protector is 20 μM, the thickness of the polymer is 12 μM, and the mass of the iron-based alloy substrate is 4.5-5 mg; or wherein the thickness of the alkaline protector is 20 μM, the thickness of the polymer is 8 μM, and the mass of the iron-based alloy substrate is 4.5-5 mg.