US 12,324,870 B2
Nasolacrimal duct insertion member comprising shape memory polymer
Hak-Joon Sung, Seoul (KR); Jin Sook Yoon, Seoul (KR); Jung Bok Lee, Seoul (KR); Jae Sang Ko, Seoul (KR); and Woo Beom Shin, Seoul (KR)
Assigned to TMD LAB CO., LTD, Seoul (KR)
Appl. No. 17/281,666
Filed by TMD LAB CO., LTD., Seoul (KR)
PCT Filed Oct. 1, 2019, PCT No. PCT/KR2019/012824
§ 371(c)(1), (2) Date Mar. 31, 2021,
PCT Pub. No. WO2020/071732, PCT Pub. Date Apr. 9, 2020.
Claims priority of application No. 10-2018-0117796 (KR), filed on Oct. 2, 2018.
Prior Publication US 2021/0369920 A1, Dec. 2, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61L 29/14 (2006.01); A61L 29/04 (2006.01); C08G 63/08 (2006.01); C08L 67/04 (2006.01); C08L 67/06 (2006.01); C08L 67/07 (2006.01)
CPC A61L 29/041 (2013.01) [A61L 29/14 (2013.01); C08G 63/08 (2013.01); A61L 2400/16 (2013.01); C08G 2280/00 (2013.01)] 5 Claims
OG exemplary drawing
 
1. A tubular device for expanding nasolacrimal duct,
wherein the device has a restored cross-sectional thickness of 50 to 200 μm, a restored inner diameter of 0.4 to 1.2 mm, and a restored length of 10 to 50 mm within the nasolacrimal duct upon exposure to physiological temperature of 28 to 42° C., and
wherein the device comprises a shape memory polymer represented by the following Chemical Formula 1:

OG Complex Work Unit Chemistry
wherein,
R1, R2, and R3 are each independently hydrogen (H) or an alkyl of 1 to 6 carbon atoms,
m and n are each an integer of 1 to 20,
A, B1, and B2 are each independently oxygen (O) or sulfur(S),
x and y represent mole % for respective repeat units, and
x+y is 100, and x is 80 to 95.
 
5. The tubular device of claim 1, comprising a shape memory polymer represented by the following Chemical Formula 2:

OG Complex Work Unit Chemistry
wherein,
m and n are each an integer of 1 to 20,
x and y represent mole % for respective repeat units, and
x+y is 100, and x is 80 to 95.