US 12,324,848 B2
Core shell silica particles and uses thereof as an anti-bacterial agent
Guisheng Pan, Philadelphia, PA (US); and Suman Chopra, Monroe, NJ (US)
Assigned to Colgate-Palmolive Company, New York, NY (US)
Filed by Colgate-Palmolive Company, New York, NY (US)
Filed on May 10, 2022, as Appl. No. 17/740,426.
Application 17/740,426 is a continuation of application No. 16/512,472, filed on Jul. 16, 2019, granted, now 11,324,678.
Application 16/512,472 is a continuation of application No. 15/106,445, granted, now 10,369,091, issued on Aug. 6, 2019, previously published as PCT/US2014/071298, filed on Dec. 18, 2014.
Claims priority of provisional application 61/918,925, filed on Dec. 20, 2013.
Claims priority of provisional application 61/918,938, filed on Dec. 20, 2013.
Prior Publication US 2022/0265535 A1, Aug. 25, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 8/25 (2006.01); A61K 8/02 (2006.01); A61K 8/19 (2006.01); A61K 8/46 (2006.01); A61Q 11/00 (2006.01); C01B 33/18 (2006.01); C03C 15/00 (2006.01); C03C 17/22 (2006.01); C03C 17/23 (2006.01); C09C 1/30 (2006.01); C09K 3/14 (2006.01)
CPC A61K 8/25 (2013.01) [A61K 8/022 (2013.01); A61K 8/0241 (2013.01); A61K 8/0245 (2013.01); A61K 8/0258 (2013.01); A61K 8/19 (2013.01); A61K 8/466 (2013.01); A61Q 11/00 (2013.01); C01B 33/18 (2013.01); C03C 15/00 (2013.01); C03C 17/22 (2013.01); C03C 17/23 (2013.01); C09C 1/3054 (2013.01); C09K 3/1436 (2013.01); C09K 3/1445 (2013.01); A61K 2800/28 (2013.01); A61K 2800/621 (2013.01); A61K 2800/651 (2013.01); A61K 2800/92 (2013.01); C01P 2004/61 (2013.01); C01P 2004/84 (2013.01)] 19 Claims
OG exemplary drawing
 
1. An oral care composition comprising:
core shell silica particles, wherein each core shell silica particle comprises a silica core and a surface of the silica core etched with group I metal silicate, wherein the core shell silica particles have a d(0.5) value that is less than the mean diameter of a human dentin tubule;
an orally acceptable carrier; and
a source of fluoride ions.