US 12,324,808 B2
Methods for the prevention and treatment of hearing loss
Jian Zuo, Carlsbad, CA (US); Zhuo Li, Omaha, NE (US); and Marisa Laura Zallocchi, Omaha, NE (US)
Assigned to Tiny Therapeutics, Inc, San Diego, CA (US)
Filed by Ting Therapeutics, Inc., San Diego, NE (US)
Filed on Dec. 19, 2022, as Appl. No. 18/084,033.
Application 18/084,033 is a continuation of application No. PCT/US2021/041197, filed on Jul. 10, 2021.
Claims priority of provisional application 63/050,568, filed on Jul. 10, 2020.
Prior Publication US 2023/0285401 A1, Sep. 14, 2023
Int. Cl. A61P 27/16 (2006.01); A61F 11/00 (2022.01); A61K 31/122 (2006.01); A61K 31/165 (2006.01); A61K 31/167 (2006.01); A61K 31/397 (2006.01); A61K 31/506 (2006.01); A61K 31/513 (2006.01); A61K 31/517 (2006.01); A61K 31/5377 (2006.01); A61K 31/609 (2006.01); A61K 31/7036 (2006.01); A61K 33/243 (2019.01); A61K 45/06 (2006.01)
CPC A61K 31/5377 (2013.01) [A61F 11/00 (2013.01); A61K 31/122 (2013.01); A61K 31/165 (2013.01); A61K 31/167 (2013.01); A61K 31/397 (2013.01); A61K 31/506 (2013.01); A61K 31/513 (2013.01); A61K 31/517 (2013.01); A61K 31/609 (2013.01); A61K 31/7036 (2013.01); A61K 33/243 (2019.01); A61K 45/06 (2013.01); A61P 27/16 (2018.01)] 2 Claims
 
1. A method to protect ear hair cells from death caused by an antibiotic comprising:
administering to a mammal in need thereof an effective amount of a pharmaceutical composition containing a therapeutically active agent, wherein the therapeutically active agent is fedratinib or a pharmaceutically acceptable salt thereof.