| CPC A61F 2/7812 (2013.01) [A61F 2/70 (2013.01); A61F 2/72 (2013.01); A61F 2002/5059 (2013.01); A61F 2002/5061 (2013.01); A61F 2002/5063 (2013.01); A61F 2002/5064 (2013.01); A61F 2002/6827 (2013.01); A61F 2002/704 (2013.01); A61F 2002/705 (2013.01); A61F 2002/707 (2013.01); A61F 2002/768 (2013.01); A61F 2002/769 (2013.01); A61F 2002/7818 (2013.01); A61F 2002/785 (2013.01)] | 29 Claims |

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1. A system for modulating nerve activation in a residual limb of an amputee, comprising:
a substrate configured to contact the residual limb, including:
a first polymer layer including a plurality of electrodes and conductive ink; and
a second polymer layer;
a liner attached to the substrate, wherein the substrate and the liner are configured to receive the residual limb, such that at least one of the plurality of electrodes is in electrical communication with the residual limb;
an electrode controller configured to transmit electrical current to the plurality of electrodes according to one or more inputs;
an interconnect configured for an amputee to interchangeably connect the electrode controller and the substrate when coupled with the conductive ink; and
an external user device to communicate signaling with the electrode controller, including:
a graphical user interface configured to receive the one or more inputs from the amputee, wherein a first input corresponds to selectively activating one or more of the plurality of electrodes such that nerve fibers are stimulated in the residual limb.
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