US 12,324,674 B2
Voxelization of a 3D structural medical image of a human's brain
Borana Dollomaja, Marseille (AL); Remi Vuillemot, Paris (FR); and Nicolas Gazeres, Velizy-Villacoublay (FR)
Assigned to DASSAULT SYSTEMES, Velizy Villacoublay (FR)
Filed by DASSAULT SYSTEMES, Velizy Villacoublay (FR)
Filed on Jul. 15, 2022, as Appl. No. 17/865,735.
Claims priority of application No. 21305997 (EP), filed on Jul. 16, 2021.
Prior Publication US 2023/0024878 A1, Jan. 26, 2023
Int. Cl. A61B 5/00 (2006.01); A61B 5/369 (2021.01)
CPC A61B 5/4064 (2013.01) [A61B 5/369 (2021.01); A61B 5/742 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A computer-implemented method for voxelizing a 3D structural medical image of a human's brain, each voxel being suitable for running a simulator of an electrical activity of a 3D volume of the human's brain being enclosed by the voxel, the method comprising:
obtaining a 3D structural medical image of the human's brain, the 3D structural medical image comprising a reference frame, wherein the 3D structural image stems from acquisition by a medical imaging device;
generating a voxelized 3D structural medical image;
obtaining parameters of at least one EEG electrode sensor and, for each EEG electrode sensor:
a localization in a reference frame of the voxelized 3D structural medical image, and
a sensor detection distance;
obtaining a 3D grid of voxels, each voxel of the 3D grid joining a same finite number of voxels of the voxelized 3D structural medical image, the number of voxels of the 3D grid being smaller than the number of voxels of the voxelized 3D structural medical image; and
for each voxel of the 3D grid, iteratively subdividing the voxel while the distance between the voxel and localization of any electrode sensor is smaller than or equal to the sensor detection distance and while a size of the voxel is greater than a predetermined length, each subdivided voxel joining a finite number of voxels of the voxelized 3D structural medical image.