US 12,002,203 B2
Systems and methods for assessing a likelihood of CTEPH and identifying characteristics indicative thereof
Karym El Sayed, Berlin (DE); Henry Hernaez, Pittsburgh, PA (US); Nivitha Mahesh, Murrysville, PA (US); Wei Liao, Frankfurt am Main (DE); Franco Fois, Monheim (DE); Daniel Rechsteiner, Cologne (DE); Jacob Agris, Great Neck Estates, NY (US); Mohammad Sedigh Ghamari, Jersey City, NJ (US); Xiangzhen Gao, Sterling Heights, MI (US); and Prahlad Menon Gopalakrishna, Bethel Park, PA (US)
Assigned to BAYER HEALTHCARE LLC, Whippany, NJ (US)
Appl. No. 17/434,839
Filed by BAYER HEALTHCARE LLC, Whippany, NJ (US)
PCT Filed Mar. 10, 2020, PCT No. PCT/US2020/021861
§ 371(c)(1), (2) Date Aug. 30, 2021,
PCT Pub. No. WO2020/185758, PCT Pub. Date Sep. 17, 2020.
Claims priority of provisional application 62/817,295, filed on Mar. 12, 2019.
Prior Publication US 2022/0148166 A1, May 12, 2022
Int. Cl. G06T 7/00 (2017.01); G06T 7/11 (2017.01); G06T 7/12 (2017.01); G06V 10/25 (2022.01); G06V 10/774 (2022.01); G16H 30/20 (2018.01)
CPC G06T 7/0012 (2013.01) [G06T 7/11 (2017.01); G06T 7/12 (2017.01); G06V 10/25 (2022.01); G06V 10/774 (2022.01); G16H 30/20 (2018.01); G06T 2207/20081 (2013.01); G06T 2207/30048 (2013.01); G06T 2207/30061 (2013.01)] 21 Claims
OG exemplary drawing
 
1. A system, comprising:
a processor; and
a memory storing an application program configured to perform, when executed by the processor, an operation for assessing a likelihood of chronic thromboembolic pulmonary hypertension within a subject patient based upon an analysis of characteristics indicative of chronic thromboembolic pulmonary hypertension within an imaging study of the subject patient, the operation comprising:
receiving an initial image set comprising a plurality of images from the imaging study of the subject patient and modifying one or more of the plurality of images from the initial image set to generate a modified image set comprising one or more modified images;
identifying in at least one of the modified images of the modified image set one or more characteristics of one or more anatomical structures within a cardiac region of the subject patient indicative of chronic thromboembolic pulmonary hypertension;
identifying in at least one of the modified images of the modified image set one or more characteristics of a pulmonary vasculature of the subject patient indicative of chronic thromboembolic pulmonary hypertension;
identifying in at least one of the modified images of the modified image set one or more characteristics of a chronic abnormality in a lung of the subject patient indicative of chronic thromboembolic pulmonary hypertension; and
assessing the one or more characteristics identified in the modified image set of (i) the one or more anatomical structures within the cardiac region of the subject patient indicative of chronic thromboembolic pulmonary hypertension, (ii) the pulmonary vasculature of the subject patient indicative of chronic thromboembolic pulmonary hypertension, and (iii) the chronic abnormality in the lung of the subject patient indicative of chronic thromboembolic pulmonary hypertension and computing, from this assessment, the likelihood of chronic thromboembolic pulmonary hypertension within the subject patient.