US 12,000,849 B2
Automatic analyzer
Akihisa Makino, Tokyo (JP); Hajime Yamazaki, Tokyo (JP); Keiko Yoshikawa, Tokyo (JP); Manabu Ando, Tokyo (JP); and Masahiko Iijima, Tokyo (JP)
Assigned to HITACHI HIGH-TECH CORPORATION, Tokyo (JP)
Filed by HITACHI HIGH-TECH CORPORATION, Tokyo (JP)
Filed on Nov. 19, 2021, as Appl. No. 17/530,623.
Application 17/530,623 is a continuation of application No. 16/520,437, filed on Jul. 24, 2019, granted, now 11,209,448.
Application 16/520,437 is a continuation of application No. 15/616,296, filed on Jun. 7, 2017, granted, now 10,416,179, issued on Sep. 17, 2019.
Application 15/616,296 is a continuation of application No. 14/402,906, granted, now 9,696,329, issued on Jul. 4, 2017, previously published as PCT/JP2013/064428, filed on May 24, 2013.
Claims priority of application No. 2012-131492 (JP), filed on Jun. 11, 2012.
Prior Publication US 2022/0074959 A1, Mar. 10, 2022
Int. Cl. G01N 35/02 (2006.01); G01N 21/11 (2006.01); G01N 21/82 (2006.01); G01N 33/86 (2006.01); G01N 35/00 (2006.01); G01N 35/10 (2006.01); G01N 35/04 (2006.01)
CPC G01N 35/025 (2013.01) [G01N 21/11 (2013.01); G01N 21/82 (2013.01); G01N 33/86 (2013.01); G01N 35/00584 (2013.01); G01N 35/00693 (2013.01); G01N 35/0092 (2013.01); G01N 35/1004 (2013.01); G01N 2021/115 (2013.01); G01N 2035/00425 (2013.01); G01N 2035/00673 (2013.01); G01N 2035/0094 (2013.01); G01N 2035/0097 (2013.01); G01N 2035/0437 (2013.01); G01N 2035/0453 (2013.01)] 7 Claims
OG exemplary drawing
 
1. An automatic analyzer, comprising:
a biochemical analyzer configured to perform biochemical analysis of a sample;
a blood coagulation time measuring section configured to analyze a blood coagulation time of the sample;
wherein the biochemical analyzer comprises:
a reaction disk on which a plurality of first reaction vessels are mounted;
a sample dispensing mechanism configured to dispense the sample to a first reaction vessel among the plurality of first reaction vessels;
a first reagent dispensing mechanism configured to dispense a first reagent or a diluent into the first reaction vessel; and
a first photometer configured to irradiate a first mixture solution contained in the first reaction vessel of the sample dispensed by the sample dispensing mechanism and the first reagent or the diluent dispensed by the first reagent dispensing mechanism, and to detect transmitted light or scattered light from the first mixture solution,
wherein the blood coagulation time measuring section comprises:
a second reagent dispensing mechanism configured to dispense the first mixture solution contained in the first reaction vessel, which has been subjected to transmitted light or scattered light detection by the first photometer, into a second reaction vessel disposed within a reaction vessel holder of the blood coagulation time measuring section from the first reaction vessel on the reaction disk, and to dispense a second reagent to the second reaction vessel containing the first mixture solution; and
a second photometer configured to irradiate a second mixture solution of the first mixture solution and the second reagent contained in the second reaction vessel, and to detect scattered light from the second mixture solution;
a controller; and
an amplifier, coupled to the controller, configured to amplify a signal acquired from the second photometer, and
wherein the controller is configured to:
acquire a value relating to an amount of an interfering substance contained in the sample included in the first mixture solution based on a detection result of the transmitted light or scattered light from the first mixture solution by the first photometer, and
control the amplifier to offset a zero level of the amplifier based on the value relating to the amount of the interfering substance before the measurement of the scattered light from the second mixture solution by the second photometer.