US 11,999,997 B2
Integrated device for nucleic acid detection and identification
Marc Dejohn, Santa Fe, NM (US); Robert B Cary, Santa Fe, NM (US); and Nathan J Cobb, Durham, NC (US)
Assigned to Mesa Biotech, Inc., Carlsbad, CA (US)
Filed by Mesa Biotech, Inc., San Diego, CA (US)
Filed on Jan. 21, 2022, as Appl. No. 17/581,285.
Application 17/581,285 is a continuation of application No. 16/678,973, filed on Nov. 8, 2019, granted, now 11,268,142.
Application 16/678,973 is a continuation of application No. 14/113,146, granted, now 10,519,492, issued on Dec. 11, 2019, previously published as PCT/US2012/034596, filed on Apr. 20, 2012.
Claims priority of provisional application 61/477,437, filed on Apr. 20, 2011.
Claims priority of provisional application 61/477,357, filed on Apr. 20, 2011.
Prior Publication US 2022/0145364 A1, May 12, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. C12P 19/34 (2006.01); B01L 3/00 (2006.01); C12Q 1/6844 (2018.01); C12Q 1/686 (2018.01)
CPC C12Q 1/686 (2013.01) [B01L 3/502723 (2013.01); C12P 19/34 (2013.01); C12Q 1/6844 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A platform, comprising:
a first chamber configured to receive a sample comprising a nucleic acid;
a second chamber, wherein the second chamber is connected to the first chamber via a first channel;
a first vent pocket that is connected to the second chamber via a second channel, wherein the first vent pocket is sealed by a rupturable labile membrane; and
wherein the second chamber is capable of fluid communication with a volume exterior to the first vent pocket when the rupturable labile membrane is ruptured.