CPC C07K 16/2896 (2013.01) [A61P 35/00 (2018.01); C07K 14/70596 (2013.01); C07K 16/2818 (2013.01); G01N 33/57492 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/21 (2013.01); C07K 2317/34 (2013.01); C07K 2317/54 (2013.01); C07K 2317/73 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01); G01N 2333/70596 (2013.01)] | 16 Claims |
1. A method for at least in part treating a disorder associated with CD9-expressing cells, comprising administering to an individual in need thereof a therapeutically effective amount of an antibody or functional part or functional equivalent that comprises:
a heavy chain CDR1 sequence that has at least 80% sequence identity with the sequence DYAMH (SEQ ID NO:2), and
a heavy chain CDR2 sequence that has the sequence GISWNSGSIVYADSVKG (SEQ ID NO:4), and
a heavy chain CDR3 sequence that has at least 80% sequence identity with the sequence AVSGYYPYFDY (SEQ ID NO:6), and
a light chain CDR1 sequence that has the sequence KSSQSVLYSSNNKNYLG (SEQ ID NO:8), and
a light chain CDR2 sequence that has at least 80% sequence identity with the sequence WASTRES (SEQ ID NO:10), and
a light chain CDR3 sequence that has the sequence QQYYTTP (SEQ ID NO:12);
or administering to said individual a nucleic acid molecule or functional equivalent encoding said antibody or functional part or functional equivalent, or a vector comprising said nucleic acid molecule or functional equivalent, or an isolated or recombinant cell comprising said nucleic acid molecule or functional equivalent, or a composition comprising said antibody or functional part or functional equivalent, or a composition comprising said nucleic acid molecule or functional equivalent, or a composition comprising said vector or said cell.
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