	US 11,999,789 B2
	Humanized antibodies to TNF-like ligand 1A (TL1A) and uses thereof
Jeffry D. Watkins, Encinitas, CA (US); Cindy T. Dickerson, Encinitas, CA (US); Rafael Rojas, San Marcos, CA (US); Matthew Reissman, San Diego, CA (US); Patricia McNeeley, San Diego, CA (US); Janine Bilsborough, Adelaide (AU); Bradley Henkle, West Hollywood, CA (US); and Stephan R. Targan, Santa Monica, CA (US)
Assigned to PROMETHEUS BIOSCIENCES, INC., San Diego, CA (US); and CEDARS-SINAI MEDICAL CENTER, Los Angeles, CA (US)
Filed by PROMETHEUS BIOSCIENCES, INC., San Diego, CA (US); and CEDARS-SINAI MEDICAL CENTER, Los Angeles, CA (US)
Filed on Feb. 28, 2022, as Appl. No. 17/682,922.
Application 17/682,922 is a division of application No. 17/110,004, filed on Dec. 2, 2020, granted, now 11,292,848.
Application 17/110,004 is a continuation of application No. PCT/US2020/057119, filed on Oct. 23, 2020.
Claims priority of provisional application 62/925,736, filed on Oct. 24, 2019.
Prior Publication US 2022/0259320 A1, Aug. 18, 2022
Int. Cl. C07K 16/24 (2006.01); A61P 1/04 (2006.01); C07K 16/28 (2006.01); A61K 39/395 (2006.01); C07K 14/52 (2006.01); C07K 14/525 (2006.01)

CPC C07K 16/2875 (2013.01) [A61P 1/04 (2018.01); C07K 16/241 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/40 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/56 (2013.01); C07K 2317/76 (2013.01)]

7 Claims

1. An antibody or antigen binding fragment thereof that binds to tumor necrosis factor ligand 1A (TL1A), wherein the antibody or antigen binding fragment thereof comprises: (a) a heavy chain variable region comprising the amino acid sequence of SEQ ID NO: 104 and (b) a light chain variable region comprising the amino acid sequence of SEQ ID NO: 201.